Jin-xiang Cheng (Previous Member, 2012-2013

Mary S. Easton Alzheimer's Translational Center

PhD Candidate

UCLA Dept Neurology and GRECC/ Veterans GLA

 XIang Cheng

It has been a pleasure to have XIang in our laboratory and we all were disappointed when she had to return to complete the last year of her PhD program. She worked extensively on tau transgenic Drosophila, and within a short time set up our Drosophila program, doing work on screening for efficacy of tau inhibitors. Everything she did she did with enthusiastic, fierce energy and conscientiousness. Here is one of her beautiful photos of a normal fly eye.


We wish her the best of luck on her PhD.


Xiang's prior work focuses on brain tumors particularly gliomas for which she has extensive expertise.



2001-2006 Fourth Military Medical University, clinical medicine, Medical Bachelor Degree

2006-2007 Department of Outpatients, Fourth Military Medical University, physician

2006.10-2007.1 Department of cardiology, Xijing Hospital, EEG physician

2007- Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Ph. D. Candidate

2009.5-2009.10 resident in Department of Neurosurgery, Xijing Hospital

2009.10-2010.1 intern in Department of Radiology, Xijing Hospital

  2011.2- resident in Department of Psychiartry, Xijing Hospital

Interests: Management of quality of life of cancer patients

       Quality of life in aging


 Tumor stem cells  


       Neurology, Psychology and psychotherapy

Research Skills: cell culture, immunohistochemistry, immunoflurescence, PRC, DNA and RNA electrophoresis.  


1: Cheng JX, Liu BL, Zhang X, Zhang YQ, Lin W, Wang R, Zhang YQ, Zhang HY, Xie L, Huo JL. The validation of the standard Chinese version of the European Organization for Research and Treatment of Cancer Quality of Life Core Questionnaire 30 (EORTC QLQ-C30) in pre-operative patients with brain tumor in China. BMC Med Res Methodol. 2011 Apr 22;11:56. PubMed PMID: 21513533; PubMed Central PMCID: PMC3112193. 

2: Cheng JX, Liu BL, Zhang X, Lin W, Zhang YQ, Liu WP, Zhang JN, Lin H, Wang R, Yin H. Health-related quality of life in glioma patients in China. BMC Cancer. 2010 Jun 18;10:305. PubMed PMID: 20565883; PubMed Central PMCID: PMC2910687.

3: Cheng JX, Liu BL, Zhang X. How powerful is CD133 as a cancer stem cell marker in brain tumors? Cancer Treat Rev. 2009 Aug;35(5):403-8. Epub 2009 Apr 14. Review. PubMed PMID: 19369008.

4: Cheng JX, Zhang X, Liu BL. Health-related quality of life in patients with high-grade glioma. Neuro Oncol. 2009 Feb;11(1):41-50. Epub 2008 Jul 15. Review. PubMed PMID: 18628405; PubMed Central PMCID: PMC2718958.

5:Liu WP, Cheng JX, Yi XC, Zhen HN, Fei Z, Li Q, Zhang X. Chordoid glioma: a case report and literature review. Neurologist. 2011 Jan;17(1):52-6. PubMed PMID: 21192197.

6: Liu BL, Cheng JX, Zhang X, Wang R, Zhang W, Lin H, Xiao X, Cai S, Chen XY, Cheng H. Global histone modification patterns as prognostic markers to classify glioma patients. Cancer Epidemiol Biomarkers Prev. 2010 Nov;19(11):2888-96. Epub 2010 Sep 14. PubMed PMID: 20978174.

7: Liu BL, Cheng JX, Zhang W, Zhang X, Wang R, Lin H, Huo JL, Cheng H. Quantitative detection of multiple gene promoter hypermethylation in tumor tissue, serum, and cerebrospinal fluid predicts prognosis of malignant gliomas. Neuro Oncol. 2010 Jun;12(6):540-8. Epub 2010 Feb 13. PubMed PMID: 20154338; PubMed Central PMCID: PMC2940650.

8: Liu BL, Cheng JX, Zhang X, Zhang W. Controversies concerning the application of brachytherapy in central nervous system tumors. J Cancer Res Clin Oncol. 2010 Feb;136(2):173-85. Review. PubMed PMID: 19956971.

9: Liu BL, Cheng JX, Zhang X, Zhang W, Cheng H. Limited role of surgery in the management of primary central nervous system lymphoma (Review). Oncol Rep. 2009 Sep;22(3):439-49. Review. PubMed PMID: 19639187.

10: Zhang X, Zhang W, Fu LA, Cheng JX, Liu BL, Cao WD, Fei Z, Zhang JN, Liu WP, Zhen HN. Hemorrhagic pituitary macroadenoma: characteristics, endoscopic endonasal transsphenoidal surgery, and outcomes. Ann Surg Oncol. 2011 Jan;18(1):246-52. Epub 2010 Aug 12. PubMed PMID: 20703818.

11: Zhang LH, Yang XL, Zhang X, Cheng JX, Zhang W. Association of elevated GRP78 expression with increased astrocytoma malignancy via Akt and ERK pathways. Brain Res. 2011 Jan 31;1371:23-31. Epub 2010 Nov 25. PubMed PMID: 21112319.

12: Lin H, Zhang X, Cheng G, Tang HF, Zhang W, Zhen HN, Cheng JX, Liu BL, Cao WD, Dong WP, Wang P. Apoptosis induced by ardipusilloside III through BAD dephosphorylation and cleavage in human glioblastoma U251MG cells. Apoptosis. 2008 Feb;13(2):247-57. PubMed PMID: 18181022.

13. Cao L, Cao W, Zhang W, Lin H, Yang X, Zhen H, Cheng J, Dong W, Huo J, Zhang X. Identification of 14-3-3 protein isoforms in human astrocytoma by immunohistochemistry. Neurosci Lett. 2008 Feb 20;432(2):94-9. Epub 2007 Dec 15.

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